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Diabetes Insipidus & SIADH

 

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Using the resources you have in your text and that are available on the web, examine the pathophysiology of diabetes insipidus and SIADH.

Case Presentation Related Pathophysiology
Steve L., a 17 year old male is admitted to the Intensive Care Unit with a closed head injury secondary to a motor vehicle accident.  Within 24 hours Steve's urine output is 8 liters a day, electrolytes are within normal limits.

What disorder do you suspect? Why?

 

 

 

 

 

 

 

 

 

 

Franklin J., a 57 year old executive, has been recently diagnosed with oat cell carcinoma of the lung.  For the past few days he has experienced increased thirst, anorexia, and fatigue. Today, he is complaining of abdominal cramps and vomiting. His electrolytes indicate hyponatremia.

What disorder do you suspect? Why?

 

 

 

 

 

 

 

 

 

 

 

Betty G., a 46 year old female, has been on thioridazine (an oral hypoglycemic drug) for several weeks. Today she is brought to your emergency room confused, lethargic and complaining of abdominal pain.  You also notice a facial muscle twitch in your examination of the patient. Her family reports that she has not felt well the past few days, complaining of anorexia and fatigue.

What disorder do you suspect? Why?

 

 

 

 

 

 

 

 

 

 

 

 

 

Marvin S., a 38 year old schizophrenic patient in a local mental hospital, is brought to the emergency room. He appears thirsty all of the time. His urine output is around 17 liters per day. He has been found drinking water from toilets and drinking other patient's liquids. He is not very communicative and will not explain why he is so thirsty.

What disorder do you suspect? Why?