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Using the resources you have in your text and that are available on the web, examine the pathophysiology of muscular dystrophy.
| Case Presentation | Identify the type of MD, it's Pathophysiology, & Genetic Implications |
| Sandy J. presents to your clinic complaining of weakness in her arms and shoulders. She is 15 years old. Her mother reports that Sandy's eyes have never completely closed when she was asleep. She reports no leg weakness. |
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| Keith P.'s mother is concerned about his increasing difficulty in walking. Keith is 4 years old. He frequently falls, stumbles, and complains of his legs being tired. This has gotten progressively worse over the past few months. Initial lab work indicates a high creatine kinase. |
How will this disease progress over the years?
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| Lyle L. comes to the infirmary at student health services because of increasing weakness in his legs - particularly when trying to climb the stairs to his dorm. He reports that he is frequently late to class because he just can't walk fast enough to get from one building to another without "cramping up". He reports that he has always had some trouble with athletics, but he really wasn't interested in sports. |
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| Terri F., age 38, reports that she has been "clumsy" since adolescence. She frequently falls and experiences some muscle weakness. She recently has noticed some mild shortness of breath, a fast heart rate, and feeling tired all the time. Terri has no children. |
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